Biomedical scences Essay Example | Topics and Well Written Essays - 3250 words

Biomedical scences - Essay Example D is inherited as the Mendelian dominant trait while d is inherited as the recessive trait. The RBCs which bear the D and Dd isotypes are referred to as Rh+ individuals and persons having the d isotype are referred to as Rh- individuals. Almost all of the Rh+ people have the D isotype and similarly the Rh- individuals have the d isotype. When the Rh+ blood is transfused to an Rh- person then anti-Rh factor will develop in the patient’s blood within 12 days. If there is a second transfusion of the same blood (Rh+ blood) to that person then cross reaction with Rh factor and anti-Rh factor will cause agglutination reactions leading to hemolytic diseases of adults and newborn. If the mother is rhesus negative and the fetus is rhesus positive (the RBC contains Rhesus antigen inherited from a rhesus positive father), then antibodies will be formed against the rhesus antigen (in the fetus) and will cross the placenta and enter the mother’s blood. In the first pregnancy there w ill be no issues but during the second pregnancy these antibodies will cross the placenta and cross react with the Rhesus antigens of the fetus carried during the second pregnancy and cause agglutination reactions. This will cause erythroblastosis fetalis leading to hemolytic anemia and sometimes deposition of unconjugated bilirubin (derived from the breakdown of hemoglobin from the lysis of RBC’s) in the basal ganglia leading to neural deficits (Chatterjee, 2004). 2. All the six Rh agglutinogens namely the C, c, D, d, E and e are involved in the hemolytic reactions and are of the delayed type. Although routine blood group tests has eliminated the risk of compatibility of RhD isotype but the other isotypes may lead to sensitization in cases of diseases like sickle cell anemia. This disease is prevalent in blacks who express the E antigen and hence produce the anti-E agglutinins which lead to difficulties of donor selection in them for transfusion purposes as in sickle

Urban Geography of Tokyo City Essay Example | Topics and Well Written Essays - 1000 words

Urban Geography of Tokyo City - Essay Example    Development of Tokyo can be linked to its demographic and economic structure. The demographic structure is the study of a given population relating to employment, age, income, relation, and population among others. However, economic structure defines the balance of output, employment, and income among other factors relating to the economic sectors. Economic sectors include primary, tertiary, secondary, and quaternary sectors. Since Tokyo's is a metropolitan, its urban geography can be analyzed by comparing its population to that of Japan, focusing on its aged population, and considering its industrial sector.  In 2012, Tokyo’s population was approximately about 13.216 million. The population is a tenth of Japans’ total population. It is, therefore, the most populous prefecture out of the forty-seven ones that make up Japan. Tokyo has an area of approximately 2,189 kilometres squared which is equal to 0.6 % of the area of Japan. The figure makes the population den sity of Tokyo to be about 6,038 people per kilometres squared making it the most densely populated Japan’s prefecture. The statistics make Tokyo extremely populated compared to Japan. The population of the aged persons in Tokyo exceeds the standard set by United Nations. According to the United Nation's standard, the aged society in a given country should not exceed the 14 % mark.The Tokyo's "aged population" is approximately 20.14 % of the total population of the city. The percentage exceeds the recommended mark by 6.14% that is a huge margin.  

Grignard arylation Lab Report Example | Topics and Well Written Essays - 750 words

Grignard arylation - Lab Report Example In this reaction, the C=O bond the ketones is attacked by the Grignard reagent to yield an alkoxide ion. The alkoxide ion formed is then protonated by H+ to form alcohol and MgBrOH (McMurry): A 50-mL round-bottomed flask containing 20 mmol of magnesium turnings and a stirbar was flame dried. A rubber stopper was affixed to the flask after it had cooled and then assembled with an addition funnel from the oven before it had cooled. Grease was applied to the glass-to-glass joints to prevent them from freezing as the parts cooled. The addition funnel was charged with a solution of phenyl bromide (20 mmol) in anhydrous ether (15 mL). 1 mL of the solution formed was then added into the flask and stirred until the reaction started. Once the reaction had begun, the rest of the phenyl bromide solution was dripped in over several minutes, at a rate that maintained a gentle reflux. Following the addition, the reaction was allowed to proceed for 20 minutes. During this period, heat was added to maintain the reflux. The Grignard reagent was allowed to cool. A solution of cyclopentanone (13 mmol) in anhydrous ether (10 mL) was added through the addition funnel while stirring. The reaction mixture was worked-up as follows: a sufficient amount of 3M HCl was added to acidify the reaction mixture. The aqueous layer that formed was extracted with CH2Cl2. While swirling, the combined organic layers were washed with 10 mL of 10% aqueous sodium bisulfite and 10 mL of brine. The organic layer was dried and the solvent obtained evaporated over a steambath. The residue obtained was stored in a shell-vial with a well-fitting cap. The workup was repeated by my partner; however, he used 20 mL of 10% aqueous NH4Cl in place of 3M HCl. In the second week of the laboratory session, the evaporation residue was transferred into a flask, after which it was vacuum distilled into a tarred flask. The product obtained was then characterized by

Supply Chain Use Case Analysis Essay Example for Free

Supply Chain Use Case Analysis Essay The final assignment for the course is a Final Paper on two cases. The Final Paper should demonstrate understanding of the reading as well as the implications of new knowledge. The eight- to ten-page paper should integrate readings and course discussions into work and life experiences. It may include an explanation and examples from previous experiences as well as implications for future applications. Read the case study at the end of Chapter 15 and the case study at the end of Chapter 16, and thoroughly answer all the following questions. Supplement your answers with scholarly research using the Ashford Online Library. Each case study should be addressed in four to five pages, resulting in a combined Final Paper of eight to ten pages. Chapter 15 Case Study: The Realco Breadmaster 1. Develop a master production schedule for the breadmaker. What do the projected ending inventory and available-to-promise numbers look like? Has Realco â€Å"overpromised†? In your view, should Realco update either the forecast or the production numbers? 2. Comment on Jack’s approach to order promising. What are the advantages? The disadvantages? How would formal master scheduling improve this process? What organizational changes would be required? 3. Following up on Question 2, which do you think is worse, refusing a customer’s order upfront because you don’t have the units available or accepting the order and then failing to deliver? What are the implications  for master scheduling? 4. Suppose Realco produces 20,000 breadmakers every week, rather than 40,000 every other week. According to the master schedule record, what impact would this have on average inventory levels? Chapter 16 Case Study: A Bump https://bitly.com/12C3yhI It is important to remember that college is not all about studying. College is a significant step into adulthood and should be treated as such. While you should not party the night away, do not keep your nose in your books to the point that you do not get to enjoy this time of your life. Business General Business Focus of the Final Paper The final assignment for the course is a Final Paper on two cases. The Final Paper should demonstrate understanding of the reading as well as the implications of new knowledge. The eight- to ten-page paper should integrate readings and course discussions into work and life experiences. It may include an explanation and examples from previous experiences as well as implications for future applications. Read the case study at the end of Chapter 15 and the case study at the end of Chapter 16, and thoroughly answer all the following questions. Supplement your answers with scholarly research using the Ashford Online Library. Each case study should be addressed in four to five pages, resulting in a combined Final Paper of eight to ten pages. Chapter 15 Case Study: The Realco Breadmaster 1. Develop a master production schedule for the breadmaker. What do the projected ending inventory and available-to-promise numbers look like? Has  Realco â€Å"overpromised†? In your view, should Realco update either the forecast or the production numbers? 2. Comment on Jack’s approach to order promising. What are the advantages? The disadvantages? How would formal master scheduling improve this process? What organizational changes would be required? 3. Following up on Question 2, which do you think is worse, refusing a customer’s order upfront because you don’t have the units available or accepting the order and then failing to deliver? What are the implications for master scheduling? 4. Suppose Realco produces 20,000 breadmakers every week, rather than 40,000 every other week. According to the master schedule record, what impact would this have on average inventory levels?

Views on Poetry and Other Art Forms in Emersons The Poet :: Emerson Poet Essays

Views on Poetry and Other Art Forms in Emerson's The Poet Emerson's "The Poet: An Essay," is packed with statements, and ideas that contradict each other in many ways. His use of lofty language and ego driven ideals are built to confuse the average reader and are clearly not meant for the purpose of entertainment. As a reader, I found the text to be confusing and unfounded in its theories about man's connection with nature. Firstly, Emerson starts right off by throwing a wrench in his own works. His description of admirers of fine art and sculpture is nothing more than a generalization. One cannot make such sweeping statements about a group of people. There are always exceptions to the rule. I am sure that many admirers of fine art know a lot about the subject and have very good reasons for liking what they do. Not only does Emerson slam the artistic elite, but his whole essay is an embodiment of the ideals he is trying to dispel in these first few sentences. Emerson treats poetry in the exact same manner in which he scoffs at in the beginning of the essay. The author feels that The "true poet" is our closest connection with nature. I am very sure that there are people who admire paintings of a fine nature scene, and they surely feel that it is our closest connection with nature. Words are not the only way to express oneself in a connecting way with nature. This brings me to another sweeping generalization that Emerson makes in the body of this essay. He actually makes the statement that words to a song are not poetry in a sense. Being a musician, I strongly disagree with such a statement. Song lyrics can be just as touching as any other type of poetry. In fact, this type of poetry has another added bonus besides the words. This is called music! Music itself can even stand alone in painting a very vibrant picture of nature with no words at all. This is more of an accomplishment, because the author is not allowed to use words in his sound painting. Music that describes nature without the use of language is still using symbolism to convey the connection between man and nature. The difference is that a violin might symbolize the wind instead of a bunch of words.

The Function of Themes in Catch-22 Essay -- Essays Papers

The Function of Themes in Catch-22 Joseph Heller produced many works of literature throughout his lifetime; however, his most acclaimed novel, Catch-22, has become a cult class among readers throughout the world. Catch-22 is not a bland novel that invokes few emotions from its readers. It is a moving novel stacked full of many themes. These themes indubitably conjure up fear and mistrust of the system that seeks to destroy one's own life. Joseph Heller was born on May 1, 1923, in the Coney Island section of Brooklyn, New York, to Russian-Jewish immigrants. His father Isaac (Pinsker 228), a bakery truck driver, died when Heller was only four years of age (Kaupunginkirjasta online). During World War II, Heller served as a bombardier for the United States Air Force and flew sixty bombing missions while stationed in Italy. This gave him the background for Catch-22 (Classic online). Specifically, while on a combat mission, Heller witnessed one of his fellow airmen die of wounds; this ultimately led to Heller's graphic portrayal of Snowden, a young airman in Catch-22, who dies a horrid death during a bombing run (Pinsker 383). After being discharged from the Air Force, Heller enrolled in the University of Southern California and later transferred to New York University where he majored in English. Upon finishing his studies in New York, Heller attended Columbia University until 1949, when he received his Master of the Arts Degree in English (Pinsker 383). After receiving his degree, Heller went on to become a professor at Pennsylvania State University where he taught English for two years (Classic online). In 1961, after a series of jobs working for such magazines as Time and Look, Heller published Catch-22, which he had been working on since 1953(Classic online). After Catch-22 was published in 1961 (Kaupunginkirjasta online), Heller continued his writing career with Something Happened in 1974, Good as Gold in 1974, God Knows in 1984, Picture This in 1988, and Closing Time in 1994 (Pinsker 379). Although not as well received as Catch-22, Closing Time serves as a sequel to Catch-22 in which the heroes are described forty years after the original novel (Kaupunginkirjasta online). Sadly on December 3, 1999, Joseph Heller died of a heart attack at his home in Long Island, New York (Kaupunginkirjasta online). Heller's career and personality was best describe... ...ecision: The Contemporary American Novel and Its Intellectual Background." Riley 228-229. Burhans, Clinton S. "Spindrift and the Sea: Structural Patterns and Unifying Elements in Catch-22." Riley 230. Calhoun High School English Department. Catch-22. Bellmore Merrick Central High School District. . 26 Oct. 2001. "Classic Notes: Joseph Heller." Classic Notes. 2001. Grade Saver. . 12 Oct. 2001. Karl, Fredrick R. "Joseph Heller's Catch-22: Only Fools Walk in Darkness." Contemporary American Novelists. Ed. Harry T More. Illinois: Southern Illinois University Press, 1964. 134-142. Kaupunginkirjasta, Kuusankosken. "Joseph Heller (1923-199)". Pegasos-Literature Related Sources. 2000. . 12 Oct. 2001. Olderman, Raymond M. "The Grail Knight Departs." Riley 229-230. Pinsker, Sanford. "Joseph Heller." American Writers. Ed. Litz, A Walton. Supplement 4, part 1. New York: Charles Scribner's Sons, 1996. 379-396. Prescott, Orville. "Books of The Times." The New York Times on the Web. 1998. . 14 Oct. 2001. Riley, Carolyn. Contemporary Literary Criticism. Detroit: Gale Research Co. 1973. "Themes PinkMonkey.com-Catch-22 by Joseph Heller." Pink Monkey.com. . 14 Oct. 01

Idling Engine Ban

1. To what extent do you agree with the idling engine ban? A few years ago, the Environmental Protection Department proposed to legislate the idling engine ban, under which all vehicles must switch off their engines. I totally disagree with the idling engine ban, for I think that this policy not only cannot bring benefits to pedestrians in air quality, but instead brings harm to drivers and passengers. To start with, the idling engine ban brings inconvenience to drivers. As the idling engine ban proposes that a driver has to switch off their idle engines immediately, drivers had to switch of their engines even if they had to wait in a place for as short as 3 minutes. This abrupt switching off and on of the engine is not only bothersome to drivers, but may lead to a shorter lifespan of motor vehicles. Apart from the harm to the driver, a problem of poor ventilation is caused by the idling engine ban, which affects both drivers and passengers. As stated by the government, vehicles are the second largest local source of air pollutants. In the middle of the road where traffic is intense, if a driver has to switch off the air conditioner and open the windows, the driver and the passengers will breathe in harmful gases which will affect their health in the long term. Also, when the temperature reaches above 30 degrees in summer, drivers and passengers have a high chance of suffering from heat strokes if the air conditioner is turned off. To maintain a driver’s good condition of health is crucial when driving, therefore the idling engine ban is not feasible. Moreover, from the government’s perspective, it is difficult for the idling engine ban to be implemented. Firstly, a fine of $320 may not be severe enough to stop drivers from switching on their idling engines. Secondly, as there are many exemptions to the ban, the police will not be able to identify violating vehicles effectively. The usefulness of the ban would be greatly decreased. The government stated that the idling engine ban can reduce air pollution in Hong Kong as vehicles are a main pollutant. I agree that the ban can improve the health of Hong Kong citizens and pedestrians in particular, though only in a small extent. However, statistics show that emissions produced when vehicles are idle are only a small part of gas emitted by vehicles. In fact, running vehicles produce a major part of pollutants. Thus, I think that the idling engine ban is not significant enough; the government should consider alternatives to tackle the major problem of the increasing number of private cars to reduce air pollution. To conclude, the idling engine ban would cause inconvenience to drivers and affect the health of drivers and pedestrians. It would be difficult to implement and ineffective to reduce air pollution. Therefore, I totally disagree with the idling engine ban as it brings harmful effects to all stakeholders. 2. What can individuals, private organizations and the government do to ease the costs you have identified in Q1? In Q1, I have identified the costs of the idling engine ban as inconvenience to drivers, poor ventilation during hot weather, difficult implementation and insignificance in reducing air pollution. Firstly, if the idling engine ban was implemented, individual drivers can develop more self-discipline and abide to the laws so that gas emissions will decrease. They can also report on cases of violating the ban. The effectiveness of the ban would increase and implementation of the ban would be more successful. Individuals can also ride on public vehicles more often, so that the major source of air pollutants would be cut down. Secondly, private organizations such as environmental organizations can tell Hong Kong citizens the benefits of the idling engine ban through large-scale functions or advertisements, so that more drivers will see the meaning behind the ban and will not complain that it is inconvenient. They will obey the ban more strictly. Thirdly, the government can ease the poor ventilation during hot weather by changing the ban to allow exemption of all vehicles from switching off the idle engine when the temperature is over 30 degrees. Also, the government can increase the fine so that drivers would not violate the ban easily and it would be easier to implement the ban.